Caricamento...
Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers
Twenty years after the thalidomide disaster in the late 1950s, Blaschke et al. reported that only the (S)-enantiomer of thalidomide is teratogenic. However, other work has shown that the enantiomers of thalidomide interconvert in vivo, which begs the question: why is teratogen activity not observed...
Salvato in:
| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6244226/ https://ncbi.nlm.nih.gov/pubmed/30459439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35457-6 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|