Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

Over the last few years, thalidomide has become one of the most important anti-tumour drugs for the treatment of relapsed-refractory multiple myeloma. However, besides its undesirable teratogenic side effect, its configurational instability critically limits any further therapeutic improvements of t...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tokunaga, Etsuko, Akiyama, Hidehiko, Soloshonok, Vadim A., Inoue, Yuki, Hara, Hideaki, Shibata, Norio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538663/
https://ncbi.nlm.nih.gov/pubmed/28763493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182152
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