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METABOLIC CROSS-TALK BETWEEN ER, MITOCHONDRIA, AND NUCLEUS: POSSIBLE IMPACT IN AGING
Nε-lysine acetylation in the lumen of the endoplasmic reticulum (ER) regulates quality control and proteostasis within the secretory pathway. Mechanistically, it has been established that the import of acetyl-CoA into the ER lumen by the membrane transporter AT-1/SLC33A1 is an essential biochemical...
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| Pubblicato in: | Innov Aging |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6243771/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.939 |
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