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METABOLIC CROSS-TALK BETWEEN ER, MITOCHONDRIA, AND NUCLEUS: POSSIBLE IMPACT IN AGING

Nε-lysine acetylation in the lumen of the endoplasmic reticulum (ER) regulates quality control and proteostasis within the secretory pathway. Mechanistically, it has been established that the import of acetyl-CoA into the ER lumen by the membrane transporter AT-1/SLC33A1 is an essential biochemical...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Dieterich, I.A., Yu, Q., Overmyer, K., Coon, J., Li, L., Puglielli, L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243771/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.939
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