Bifunctional amyloid-reactive peptide promotes binding of antibody 11-1F4 to diverse amyloid types and enhances therapeutic efficacy

Amyloidosis is a malignant pathology associated with the formation of proteinaceous amyloid fibrils that deposit in organs and tissues, leading to dysfunction and severe morbidity. More than 25 proteins have been identified as components of amyloid, but the most common form of systemic amyloidosis i...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wall, Jonathan S., Williams, Angela D., Foster, James S., Richey, Tina, Stuckey, Alan, Macy, Sallie, Wooliver, Craig, Campagna, Shawn R., Tague, Eric D., Farmer, Abigail T., Lands, Ronald H., Martin, Emily B., Heidel, R. Eric, Kennel, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243252/
https://ncbi.nlm.nih.gov/pubmed/30377267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805515115
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