Bifunctional amyloid-reactive peptide promotes binding of antibody 11-1F4 to diverse amyloid types and enhances therapeutic efficacy

Amyloidosis is a malignant pathology associated with the formation of proteinaceous amyloid fibrils that deposit in organs and tissues, leading to dysfunction and severe morbidity. More than 25 proteins have been identified as components of amyloid, but the most common form of systemic amyloidosis i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wall, Jonathan S., Williams, Angela D., Foster, James S., Richey, Tina, Stuckey, Alan, Macy, Sallie, Wooliver, Craig, Campagna, Shawn R., Tague, Eric D., Farmer, Abigail T., Lands, Ronald H., Martin, Emily B., Heidel, R. Eric, Kennel, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243252/
https://ncbi.nlm.nih.gov/pubmed/30377267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805515115
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