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Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice

OBJECTIVE: Determine the role of phagocytosis in the deposition of acute phase SAA protein in peripheral organs as AA amyloid. METHODS: AA amyloidosis was induced by injection of amyloid enhancing factor (AEF) in huIL-6 transgenic mice. Clodronate liposomes were injected at different times, and the...

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Bibliografiset tiedot
Päätekijät: Kennel, Stephen J., Macy, Sallie, Wooliver, Craig, Huang, Ying, Richey, Tina, Heidel, Eric, Wall, Jonathan S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112139/
https://ncbi.nlm.nih.gov/pubmed/24446872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2013.876400
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