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Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice
OBJECTIVE: Determine the role of phagocytosis in the deposition of acute phase SAA protein in peripheral organs as AA amyloid. METHODS: AA amyloidosis was induced by injection of amyloid enhancing factor (AEF) in huIL-6 transgenic mice. Clodronate liposomes were injected at different times, and the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112139/ https://ncbi.nlm.nih.gov/pubmed/24446872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2013.876400 |
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