Enhanced inter-compartmental Ca(2+) flux modulates mitochondrial metabolism and apoptotic threshold during aging

BACKGROUND: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxygen species (ROS) and executors of programmed cell d...

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Foilsithe in:Redox Biol
Main Authors: Madreiter-Sokolowski, Corina T., Waldeck-Weiermair, Markus, Bourguignon, Marie-Pierre, Villeneuve, Nicole, Gottschalk, Benjamin, Klec, Christiane, Stryeck, Sarah, Radulovic, Snjezana, Parichatikanond, Warisara, Frank, Saša, Madl, Tobias, Malli, Roland, Graier, Wolfgang F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243020/
https://ncbi.nlm.nih.gov/pubmed/30458321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.11.003
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