Myeloid-derived suppressor cells control B cell accumulation in the CNS during autoimmunity

PMN-MDSCs (polymorphonuclear myeloid-derived suppressor cells) have been characterized in the context of malignancies. Here we found that PMN-MDSCs had the unique ability to restrain B cell accumulation during central nervous system (CNS) autoimmunity. Ly6G(+) cells were recruited to the CNS during...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Knier, Benjamin, Hiltensperger, Michael, Sie, Christopher, Aly, Lilian, Lepennetier, Gildas, Engleitner, Thomas, Garg, Garima, Muschaweckh, Andreas, Mitsdörffer, Meike, Koedel, Uwe, Höchst, Bastian, Knolle, Percy, Gunzer, Matthias, Hemmer, Bernhard, Rad, Roland, Merkler, Doron, Korn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241855/
https://ncbi.nlm.nih.gov/pubmed/30374128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0237-5
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