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Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs
The human chr15q11-q13 imprinted cluster is linked to several disorders, including Prader–Willi (PWS) and Angelman (AS) syndromes. Recently, disease modeling approaches based on induced pluripotent stem cells (iPSCs) have been used to study these syndromes. A concern regarding the use of these cells...
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| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240739/ https://ncbi.nlm.nih.gov/pubmed/30102380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy274 |
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