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The imprinting mechanism of the Prader–Willi/Angelman regional control center
The 2 Mb domain on chromosome 15q11–q13 that carries the imprinted genes involved in Prader–Willi (PWS) and Angelman (AS) syndromes is under the control of an imprinting center comprising two regulatory regions, the PWS-SRO located around the SNRPN promoter and the AS-SRO located 35 kb upstream. Her...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC131067/ https://ncbi.nlm.nih.gov/pubmed/12411498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf570 |
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