FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases characterized by the progressive loss of specific groups of neurons. Due to clinical, genetic and pathological overlap, both diseases are considered as the extremes of one disease spectrum and in a n...

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Detalles Bibliográficos
Publicado en:Hum Mol Genet
Main Authors: Steyaert, Jolien, Scheveneels, Wendy, Vanneste, Joni, Van Damme, Philip, Robberecht, Wim, Callaerts, Patrick, Bogaert, Elke, Van Den Bosch, Ludo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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General Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240733/
https://ncbi.nlm.nih.gov/pubmed/30379317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy303
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