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C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
Repeat expansions in the C9orf72 gene cause amyotrophic lateral sclerosis and frontotemporal dementia characterized by dipeptide-repeat protein (DPR) inclusions. The toxicity associated with two of these DPRs, poly-GR and poly-PR, has been associated with nucleocytoplasmic transport. To investigate...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6823349/ https://ncbi.nlm.nih.gov/pubmed/31673013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52035-6 |
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