Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes

Osteoarthritis (OA) is common age-associated disease, and associated with joint pain, mobility limitations and compromised overall quality of life. OA treatment is currently limited to pain management and joint arthroplasty at end stage disease. Oxidative damage to cartilage extracellular matrix and...

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Veröffentlicht in:Eur J Pharmacol
Hauptverfasser: Ishitobi, Hiroyuki, Sanada, Yohei, Kato, Yoshio, Ikuta, Yasunari, Shibata, Sachi, Yamasaki, Satoshi, Lotz, Martin K, Matsubara, Kiminori, Miyaki, Shigeru, Adachi, Nobuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240351/
https://ncbi.nlm.nih.gov/pubmed/29678719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.04.018
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