Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1

INTRODUCTION: BTB and CNC homology 1 (Bach1) is a transcriptional repressor of Heme oxygenase-1 (HO-1), which is cytoprotective through its antioxidant effects. The objective of this study was to define the role of Bach1 in cartilage homeostasis and osteoarthritis (OA) development using in vitro mod...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: Takada, Tsuyoshi, Miyaki, Shigeru, Ishitobi, Hiroyuki, Hirai, Yuya, Nakasa, Tomoyuki, Igarashi, Kazuhiko, Lotz, Martin K., Ochi, Mitsuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603301/
https://ncbi.nlm.nih.gov/pubmed/26458773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0792-1
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