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Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes

INTRODUCTION: Osteoarthritis (OA) is a whole joint disease, and characterized by progressive degradation of articular cartilage, synovial hyperplasia, bone remodeling and angiogenesis in various joint tissues. Exosomes are a type of microvesicles (MVs) that may play a role in tissue-tissue and cell-...

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Publicado en:Arthritis Res Ther
Main Authors: Kato, Tomohiro, Miyaki, Shigeru, Ishitobi, Hiroyuki, Nakamura, Yoshihiro, Nakasa, Tomoyuki, Lotz, Martin K, Ochi, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261911/
https://ncbi.nlm.nih.gov/pubmed/25092378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4679
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