Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina

In mammalian albinism, disrupted melanogenesis in the retinal pigment epithelium (RPE) is associated with fewer retinal ganglion cells (RGCs) projecting ipsilaterally to the brain, resulting in numerous abnormalities in the retina and visual pathway, especially binocular vision. To further understan...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Iwai-Takekoshi, Lena, Balasubramanian, Revathi, Sitko, Austen, Khan, Rehnuma, Weinreb, Samuel, Robinson, Kiera, Mason, Carol
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
Soggetti:
Research Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240318/
https://ncbi.nlm.nih.gov/pubmed/30254141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.163212
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