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Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina

In mammalian albinism, disrupted melanogenesis in the retinal pigment epithelium (RPE) is associated with fewer retinal ganglion cells (RGCs) projecting ipsilaterally to the brain, resulting in numerous abnormalities in the retina and visual pathway, especially binocular vision. To further understan...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Iwai-Takekoshi, Lena, Balasubramanian, Revathi, Sitko, Austen, Khan, Rehnuma, Weinreb, Samuel, Robinson, Kiera, Mason, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240318/
https://ncbi.nlm.nih.gov/pubmed/30254141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.163212
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