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Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina

In mammalian albinism, disrupted melanogenesis in the retinal pigment epithelium (RPE) is associated with fewer retinal ganglion cells (RGCs) projecting ipsilaterally to the brain, resulting in numerous abnormalities in the retina and visual pathway, especially binocular vision. To further understan...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Iwai-Takekoshi, Lena, Balasubramanian, Revathi, Sitko, Austen, Khan, Rehnuma, Weinreb, Samuel, Robinson, Kiera, Mason, Carol
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240318/
https://ncbi.nlm.nih.gov/pubmed/30254141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.163212
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