Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer

The standard treatment for metastatic prostate cancer (PCa), androgen deprivation therapy (ADT), is designed to suppress androgen receptor (AR) activity. However, men invariably progress to castration-resistant prostate cancer (CRPC), and AR reactivation contributes to progression in most cases. To...

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Publicat a:Cancer Res
Autors principals: Russo, Joshua W., Gao, Ce, Bhasin, Swati S., Voznesensky, Olga S., Calagua, Carla, Arai, Seiji, Nelson, Peter S., Montgomery, Bruce, Mostaghel, Elahe A., Corey, Eva, Taplin, Mary-Ellen, Ye, Huihui, Bhasin, Manoj, Balk, Steven P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239953/
https://ncbi.nlm.nih.gov/pubmed/30242112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0687
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