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Castration-Adapted Prostate Cancer: Targeting Androgen Metabolic Pathways in Recurrent Disease

Emerging evidence suggests that despite testicular androgen ablation, residual androgens, likely of adrenal---though potentially of prostatic---origin, play a critical role in the progression of prostate cancer to recurrent ‘castration-resistant’ disease. Thus, a reassessment of the concept of total...

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Detalhes bibliográficos
Main Authors: Mostaghel, Elahe A, Montgomery, Robert, Nelson, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705999/
https://ncbi.nlm.nih.gov/pubmed/19414113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2009.03.016
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