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Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications

Residual tissue androgens are consistently detected within the prostate tumors of castrate individuals and are thought to play a critical role in facilitating the androgen-receptor-mediated signaling pathways leading to disease progression. The source of residual tumor androgens is attributed in par...

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Detalhes bibliográficos
Main Authors: Mostaghel, Elahe A., Nelson, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474812/
https://ncbi.nlm.nih.gov/pubmed/18471783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beem.2008.01.003
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