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Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on polymer chip

A specific double-stranded DNA sensing system is of great interest for diagnostic and other biomedical applications. Zinc finger domains, which recognize double-stranded DNA, can be engineered to form custom DNA-binding proteins for recognition of specific DNA sequences. As a proof of concept, a seq...

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Detalhes bibliográficos
Publicado no:Analyst
Main Authors: Ha, Dat Thinh, Ghosh, Sthitodhi, Ahn, Chong H., Segal, David, J., Kim, Moon-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239418/
https://ncbi.nlm.nih.gov/pubmed/30043772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an00395e
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