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Sensitive and direct electrochemical detection of double-stranded DNA utilizing alkaline phosphatase-labelled zinc finger proteins

Direct detection of double-stranded DNA (dsDNA) using zinc finger proteins (ZFPs) is of great importance in biomedical applications such as identifying pathogens and circulating DNAs. However, its sensitivity is still not sufficiently high because limited signalling labels can be conjugated or fused...

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Détails bibliographiques
Publié dans:Analyst
Auteurs principaux: Noh, Soodong, Ha, Dat Thinh, Yang, Haesik, Kim, Moon-Soo
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737503/
https://ncbi.nlm.nih.gov/pubmed/25969923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an00623f
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