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Sensitive and direct electrochemical detection of double-stranded DNA utilizing alkaline phosphatase-labelled zinc finger proteins

Direct detection of double-stranded DNA (dsDNA) using zinc finger proteins (ZFPs) is of great importance in biomedical applications such as identifying pathogens and circulating DNAs. However, its sensitivity is still not sufficiently high because limited signalling labels can be conjugated or fused...

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Dettagli Bibliografici
Pubblicato in:Analyst
Autori principali: Noh, Soodong, Ha, Dat Thinh, Yang, Haesik, Kim, Moon-Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737503/
https://ncbi.nlm.nih.gov/pubmed/25969923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an00623f
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