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Acidic pH promotes nucleus pulposus cell senescence through activating the p38 MAPK pathway
Background: Nucleus pulposus (NP) cell senescence is an important cellular feature within the degenerative disc. It is known that a very acidic niche exists in the degenerative disc, which participates in regulating disc cell viability and matrix metabolism. Objective: The present study was aimed to...
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| Veröffentlicht in: | Biosci Rep |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239263/ https://ncbi.nlm.nih.gov/pubmed/30291218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181451 |
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