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Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma
PURPOSE: We evaluated prevention of transforming growth factor β (TGFβ)–induced transdifferentiation of cultured scleral fibroblasts to myofibroblasts by rho-associated protein kinase (ROCK) inhibitors. Additionally, we tested whether local delivery of ROCK inhibitors reduced scleral fibroblast prol...
में बचाया:
में प्रकाशित: | Transl Vis Sci Technol |
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मुख्य लेखकों: | , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
The Association for Research in Vision and Ophthalmology
2018
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6238981/ https://ncbi.nlm.nih.gov/pubmed/30479877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.7.6.6 |
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