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Dasatinib inhibits peripapillary scleral myofibroblast differentiation
Scleral fibroblast activation occurs in glaucomatous and myopic eyes. Here we perform an unbiased screen to identify kinase inhibitors that reduce fibroblast activation to diverse stimuli in vitro and to in vivo intraocular pressure (IOP) elevation. Primary cultures of peripapillary scleral (PPS) fi...
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Foilsithe in: | Exp Eye Res |
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Main Authors: | , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2020
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7217736/ https://ncbi.nlm.nih.gov/pubmed/32179077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.107999 |
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