Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma

PURPOSE: To determine if oral losartan treatment decreases the retinal ganglion cell (RGC) death caused by experimental intraocular pressure (IOP) elevation in mice. METHODS: We produced IOP increase in CD1 mice and performed unilateral optic nerve crush. Mice received oral losartan, spironolactone,...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Quigley, Harry A., Pitha, Ian F., Welsbie, Derek S., Nguyen, Cathy, Steinhart, Matthew R., Nguyen, Thao D., Pease, Mary Ellen, Oglesby, Ericka N., Berlinicke, Cynthia A., Mitchell, Katherine L., Kim, Jessica, Jefferys, Joan J., Kimball, Elizabeth C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624713/
https://ncbi.nlm.nih.gov/pubmed/26505191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141137
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