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Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells

The conserved and essential histone chaperone, facilitates chromatin transcription (FACT), reorganizes nucleosomes during DNA transcription, replication, and repair and ensures both efficient elongation of RNA Pol II and nucleosome integrity. In mammalian cells, FACT is a heterodimer, consisting of...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Mylonas, Constantine, Tessarz, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238418/
https://ncbi.nlm.nih.gov/pubmed/30456357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800085
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