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Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells
The conserved and essential histone chaperone, facilitates chromatin transcription (FACT), reorganizes nucleosomes during DNA transcription, replication, and repair and ensures both efficient elongation of RNA Pol II and nucleosome integrity. In mammalian cells, FACT is a heterodimer, consisting of...
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| Udgivet i: | Life Sci Alliance |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Life Science Alliance LLC
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6238418/ https://ncbi.nlm.nih.gov/pubmed/30456357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800085 |
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