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Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

The pioneer activity of transcription factors allows for opening of inaccessible regulatory elements and has been extensively studied in the context of cellular differentiation and reprogramming. In contrast, the function of pioneer activity in self-renewing cell divisions and across the cell cycle...

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Udgivet i:eLife
Main Authors: Friman, Elias T, Deluz, Cédric, Meireles-Filho, Antonio CA, Govindan, Subashika, Gardeux, Vincent, Deplancke, Bart, Suter, David M
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890464/
https://ncbi.nlm.nih.gov/pubmed/31794382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50087
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