BACE2 distribution in major brain cell types and identification of novel substrates

β-Site APP-cleaving enzyme 1 (BACE1) inhibition is considered one of the most promising therapeutic strategies for Alzheimer’s disease, but current BACE1 inhibitors also block BACE2. As the localization and function of BACE2 in the brain remain unknown, it is difficult to predict whether relevant si...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Life Sci Alliance
Päätekijät: Voytyuk, Iryna, Mueller, Stephan A, Herber, Julia, Snellinx, An, Moechars, Dieder, van Loo, Geert, Lichtenthaler, Stefan F, De Strooper, Bart
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Life Science Alliance LLC 2018
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238391/
https://ncbi.nlm.nih.gov/pubmed/30456346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800026
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