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Targeting fidelity of adenine and cytosine base editors in mouse embryos
Base editing directly converts a target base pair into a different base pair in the genome of living cells without introducing double-stranded DNA breaks. While cytosine base editors (CBE) and adenine base editors (ABE) are used to install and correct point mutations in a wide range of organisms, th...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6238002/ https://ncbi.nlm.nih.gov/pubmed/30442934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07322-7 |
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