Loading...

Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine

Adipocytes are the prevalent stromal cell type in adult bone marrow (BM), and leukemia cells continuously adapt to deficiency of nutrients acquiring chemoresistant profiles in the BM microenvironment. We have previously shown that fatty acid metabolism is a key energy pathway for survival of acute m...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tabe, Yoko, Saitoh, Kaori, Yang, Haeun, Sekihara, Kazumasa, Yamatani, Kotoko, Ruvolo, Vivian, Taka, Hikari, Kaga, Naoko, Kikkawa, Mika, Arai, Hajime, Miida, Takashi, Andreeff, Michael, Spagnuolo, Paul A., Konopleva, Marina
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237992/
https://ncbi.nlm.nih.gov/pubmed/30442990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35198-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!