Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs

Progress in oligonucleotide chemistry has produced a shift in the nature of siRNA used, from formulated, minimally modified siRNAs, to unformulated, heavily modified siRNA conjugates. The introduction of extensive chemical modifications is essential for conjugate-mediated delivery. Modifications hav...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Shmushkovich, Taisia, Monopoli, Kathryn R, Homsy, Diana, Leyfer, Dmitriy, Betancur-Boissel, Monica, Khvorova, Anastasia, Wolfson, Alexey D
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
RNA and RNA-protein complexes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237813/
https://ncbi.nlm.nih.gov/pubmed/30169779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky745
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars