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Proton tunnelling in hydrogen bonds and its implications in an induced-fit model of enzyme catalysis

The role of proton tunnelling in biological catalysis is investigated here within the frameworks of quantum information theory and thermodynamics. We consider the quantum correlations generated through two hydrogen bonds between a substrate and a prototypical enzyme that first catalyses the tautomer...

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Détails bibliographiques
Publié dans:Proc Math Phys Eng Sci
Auteurs principaux: Pusuluk, Onur, Farrow, Tristan, Deliduman, Cemsinan, Burnett, Keith, Vedral, Vlatko
Format: Artigo
Langue:Inglês
Publié: The Royal Society Publishing 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237491/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspa.2018.0037
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