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Proton tunnelling in hydrogen bonds and its implications in an induced-fit model of enzyme catalysis

The role of proton tunnelling in biological catalysis is investigated here within the frameworks of quantum information theory and thermodynamics. We consider the quantum correlations generated through two hydrogen bonds between a substrate and a prototypical enzyme that first catalyses the tautomer...

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Dades bibliogràfiques
Publicat a:Proc Math Phys Eng Sci
Autors principals: Pusuluk, Onur, Farrow, Tristan, Deliduman, Cemsinan, Burnett, Keith, Vedral, Vlatko
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237491/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspa.2018.0037
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