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Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes

Antigenic variation by variant surface glycoprotein (VSG) coat switching in African trypanosomes is one of the most elaborate immune evasion strategies found among pathogens. Changes in the identity of the transcribed VSG gene, which is always flanked by 70-bp and telomeric repeats, can be achieved...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: da Silva, Marcelo Santos, Hovel-Miner, Galadriel A., Briggs, Emma M., Elias, Maria Carolina, McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237402/
https://ncbi.nlm.nih.gov/pubmed/30440029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007321
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