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Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

African trypanosomes escape the host adaptive immune response by switching their dense protective coat of Variant Surface Glycoprotein (VSG). Each cell expresses only one VSG gene at a time from a telomeric expression site (ES). The ‘pre-genomic’ era saw the identification of the range of pathways i...

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Bibliografiske detaljer
Main Authors: Horn, David, McCulloch, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Current Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117991/
https://ncbi.nlm.nih.gov/pubmed/20884281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2010.08.009
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