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Decrease in Plasma Membrane Tension Triggers PtdIns(4,5)P(2) Phase Separation to Inactivate TORC2
The Target of Rapamycin Complex 2 (TORC2) plays a key role in maintaining the homeostasis of plasma membrane (PM) tension. TORC2 activation upon increased PM tension involves redistribution of the Slm1 and 2 paralogs from PM invaginations known as eisosomes into membrane compartments containing TORC...
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| Publicado en: | Nat Cell Biol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237274/ https://ncbi.nlm.nih.gov/pubmed/30154550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0150-z |
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