Decrease in Plasma Membrane Tension Triggers PtdIns(4,5)P(2) Phase Separation to Inactivate TORC2

The Target of Rapamycin Complex 2 (TORC2) plays a key role in maintaining the homeostasis of plasma membrane (PM) tension. TORC2 activation upon increased PM tension involves redistribution of the Slm1 and 2 paralogs from PM invaginations known as eisosomes into membrane compartments containing TORC...

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Bibliografiska uppgifter
I publikationen:Nat Cell Biol
Huvudupphovsmän: Riggi, Margot, Niewola-Staszkowska, Karolina, Chiaruttini, Nicolas, Colom, Adai, Kusmider, Beata, Mercier, Vincent, Soleimanpour, Saeideh, Stahl, Michael, Matile, Stefan, Roux, Aurélien, Loewith, Robbie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237274/
https://ncbi.nlm.nih.gov/pubmed/30154550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0150-z
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