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A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies

Zebrafish are a powerful tool for studying muscle function owing to their high numbers of offspring, low maintenance costs, evolutionarily conserved muscle functions, and the ability to rapidly take up small molecular compounds during early larval stages. Fukutin-related protein (FKRP) is a putative...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Serafini, Peter R., Feyder, Michael J., Hightower, Rylie M., Garcia-Perez, Daniela, Vieira, Natássia M., Lek, Angela, Gibbs, Devin E., Moukha-Chafiq, Omar, Augelli-Szafran, Corinne E., Kawahara, Genri, Widrick, Jeffrey J., Kunkel, Louis M., Alexander, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237228/
https://ncbi.nlm.nih.gov/pubmed/30232282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120493
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