A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies

Zebrafish are a powerful tool for studying muscle function owing to their high numbers of offspring, low maintenance costs, evolutionarily conserved muscle functions, and the ability to rapidly take up small molecular compounds during early larval stages. Fukutin-related protein (FKRP) is a putative...

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Pubblicato in:JCI Insight
Autori principali: Serafini, Peter R., Feyder, Michael J., Hightower, Rylie M., Garcia-Perez, Daniela, Vieira, Natássia M., Lek, Angela, Gibbs, Devin E., Moukha-Chafiq, Omar, Augelli-Szafran, Corinne E., Kawahara, Genri, Widrick, Jeffrey J., Kunkel, Louis M., Alexander, Matthew S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237228/
https://ncbi.nlm.nih.gov/pubmed/30232282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120493
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