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Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy

Sapje zebrafish lack the protein dystrophin and are the smallest vertebrate model of Duchenne muscular dystrophy (DMD). Their small size makes them ideal for large-scale drug discovery screens. However, the extent that sapje mimic the muscle dysfunction of higher vertebrate models of DMD is unclear....

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Publicat a:Physiol Genomics
Autors principals: Widrick, Jeffrey J., Alexander, Matthew S., Sanchez, Benjamin, Gibbs, Devin E., Kawahara, Genri, Beggs, Alan H., Kunkel, Louis M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223571/
https://ncbi.nlm.nih.gov/pubmed/27764767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00088.2016
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