Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy

Sapje zebrafish lack the protein dystrophin and are the smallest vertebrate model of Duchenne muscular dystrophy (DMD). Their small size makes them ideal for large-scale drug discovery screens. However, the extent that sapje mimic the muscle dysfunction of higher vertebrate models of DMD is unclear....

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Widrick, Jeffrey J., Alexander, Matthew S., Sanchez, Benjamin, Gibbs, Devin E., Kawahara, Genri, Beggs, Alan H., Kunkel, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Comparative, Statistical, and Computational Genomics and Model Organism Databases
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223571/
https://ncbi.nlm.nih.gov/pubmed/27764767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00088.2016
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