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Drug screening in a zebrafish model of Duchenne muscular dystrophy
Two known zebrafish dystrophin mutants, sapje and sapje-like (sap(c/100)), represent excellent small-animal models of human muscular dystrophy. Using these dystrophin-null zebrafish, we have screened the Prestwick chemical library for small molecules that modulate the muscle phenotype in these fish....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069215/ https://ncbi.nlm.nih.gov/pubmed/21402949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102116108 |
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