Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy

Sapje zebrafish lack the protein dystrophin and are the smallest vertebrate model of Duchenne muscular dystrophy (DMD). Their small size makes them ideal for large-scale drug discovery screens. However, the extent that sapje mimic the muscle dysfunction of higher vertebrate models of DMD is unclear....

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Veröffentlicht in:Physiol Genomics
Hauptverfasser: Widrick, Jeffrey J., Alexander, Matthew S., Sanchez, Benjamin, Gibbs, Devin E., Kawahara, Genri, Beggs, Alan H., Kunkel, Louis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
Schlagworte:
Comparative, Statistical, and Computational Genomics and Model Organism Databases
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223571/
https://ncbi.nlm.nih.gov/pubmed/27764767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00088.2016
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