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On-column Dimethylation with Capillary Liquid Chromatography-Tandem Mass Spectrometry for Online Determination of Neuropeptides in Rat Brain Microdialysate

We have developed a method for online collection and quantitation of neuropeptides in rat brain microdialysates using on-column dimethylation with capillary liquid chromatography - tandem mass spectrometry (cLC – MS(2)). This method addresses a number of the challenges of quantifying neuropeptides w...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Wilson, Rachael E., Jaquins-Gerstl, Andrea, Weber, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236683/
https://ncbi.nlm.nih.gov/pubmed/29504751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04965
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