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Optimization for speed and sensitivity in capillary high performance liquid chromatography. The importance of column diameter in online monitoring of serotonin by microdialysis

The speed of a separation defines the best time resolution possible in online measurements using chromatography. The desired time resolution multiplied by the flow rate of the stream of analyte being sampled defines the maximum volume of sample per injection. The best concentration sensitivity in ch...

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Detalhes bibliográficos
Main Authors: Zhang, Jing, Liu, Yansheng, Jaquins-Gerstl, Andrea, Shu, Zhan, Michael, Adrian C., Weber, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419010/
https://ncbi.nlm.nih.gov/pubmed/22771067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2012.06.002
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