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Comparing nanoflow reversed-phase liquid chromatography-tandem mass spectrometry and capillary zone electrophoresis- tandem mass spectrometry for top-down proteomics

One of the major shortcomings in top-down proteomics is the lack of efficient separations for intact proteins that can be effectively coupled to mass spectrometry. Capillary zone electrophoresis (CZE) and nanoflow reversed-phase liquid chromatography (nanoRPLC) are two methods that can be coupled to...

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Detalhes bibliográficos
Publicado no:Se Pu
Main Authors: MCCOOL, Elijah N., SUN, Liangliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545479/
https://ncbi.nlm.nih.gov/pubmed/31642259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3724/SP.J.1123.2019.05001
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